Medical Science Liaison (MSL) / Senior Medical Science Liaison (Senior MSL)

Company: Kyverna Therapeutics

Location: Remote (Ideally based in Southeast region, USA)

Travel: Approximately 50-70%

About the Company:
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company dedicated to developing cell therapies for autoimmune diseases. Guided by our core values, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation.

Position Overview:
Kyverna is seeking a Medical Science Liaison (MSL) or Senior Medical Science Liaison (Senior MSL) to join the Medical Affairs organization. This field-based role serves as a scientific expert, engaging with healthcare professionals, investigators, treatment centers, and Key Opinion Leaders (KOLs) focused on autoimmune diseases and cell therapy. The ideal candidate possesses strong scientific expertise, exceptional relationship-building skills, and experience with complex specialty therapies in biotechnology or pharmaceutical settings. This role is critical for communicating scientific and clinical data, gathering field insights, and supporting Kyverna’s CAR-T therapy programs.

Responsibilities:

Scientific Engagement & KOL Management

• Identify, establish, and maintain high-quality scientific relationships with KOLs, investigators, academic medical centers, community physicians, pharmacists, nurses, and treatment centers within the assigned territory.
• Serve as a trusted scientific partner by providing fair-balanced, accurate, and compliant scientific exchange related to disease state, treatment landscape, Kyverna’s CAR-T programs, and emerging clinical data.
• Act as a primary scientific liaison for investigators interested in clinical research collaborations and investigator-initiated research discussions, in alignment with company policies.

Territory Strategy & Field Medical Planning

• Develop and execute geography-specific Medical Affairs and KOL engagement plans aligned with therapeutic area objectives, investigator needs, and Kyverna’s medical strategy.
• Demonstrate ownership of the assigned territory through stakeholder mapping, prioritization, and proactive planning to influence the patient journey and support optimal therapeutic decision-making.
• Partner with other Kyverna field medical colleagues to share insights and coordinate external engagement approaches.

Clinical Development & Trial Support

• Collaborate with Clinical Development and Clinical Operations colleagues to support Kyverna-sponsored clinical trials, including identifying potential trial sites, engaging with participating investigators, and supporting trial awareness and scientific dialogue.
• Contribute to efforts aimed at enhancing trial feasibility and enrollment through appropriate scientific engagement with investigators and treatment centers.

Medical Insights & Internal Collaboration

• Capture and communicate timely, high-quality medical insights related to the autoimmune and cell therapy landscape to internal stakeholders to support strategy and evidence planning.
• Translate external scientific perspectives into actionable insights that inform medical, clinical, and development decision-making.
• Collaborate cross-functionally with Clinical Development, Clinical Operations, Regulatory Affairs, Commercial, Market Access, and Patient Services teams while maintaining strict non-promotional boundaries.

Scientific Representation & Compliance

• Provide scientific support at national, regional, and local congresses, advisory boards, investigator meetings, and medical education forums.
• Respond compliantly to unsolicited medical information requests and serve as an internal and external scientific resource.
• Maintain current knowledge of therapeutic areas, treatment guidelines, clinical research processes, and cell therapy operational considerations.
• Ensure timely completion of CRM documentation, administrative tasks, required training, and pharmacovigilance responsibilities.
• Conduct all activities in full compliance with applicable laws, regulations, and company policies.

Qualifications:

• Advanced scientific or clinical degree required (MD, PharmD, PhD, DNP, NP, PA, or equivalent).
• For MSL: Doctorate degree OR Master’s degree & 3 years of Medical Affairs experience.
• For Senior MSL: Doctorate degree & 2 years of Medical Affairs experience OR Master’s degree & 6 years of Medical Affairs experience.
• Prior experience in cell therapy, CAR-T, immunology, rheumatology, nephrology, neurology, hematology/oncology, or rare diseases strongly preferred.
• Strong understanding of clinical trial design, clinical development, and medical affairs functions.
• Experience engaging with academic medical centers, specialty treatment centers, and/or infusion centers preferred.
• Ability to interpret and communicate complex scientific and clinical information.
• Excellent presentation, communication, and interpersonal skills.
• Demonstrated ability to build strong external relationships and collaborate effectively across cross-functional teams.
• Comfortable operating within a fast-paced, high-growth biotechnology environment.
• Willingness and ability to travel extensively within the assigned geography.
• Experience supporting pre-commercial or launch-stage biotechnology organizations.
• Knowledge of autoimmune disease treatment landscapes and emerging cell therapy approaches.
• Experience supporting investigator-sponsored research and clinical trial recruitment initiatives.
• Familiarity with cell therapy operational concepts (chain of identity, chain of custody, treatment center workflows).

Salary Ranges:

• MSL: $170,000 - $185,000 USD annually.
• Senior MSL: $190,000 - $210,000 USD annually.

Note: These ranges are estimates. Actual salary may vary based on individual qualifications, experience, tenure, skills, and alignment with market data. This position is also eligible for bonus, benefits, and participation in the Company’s stock plan.