Medical Science Liaison (MSL) / Senior Medical Science Liaison (Senior MSL)

Company: Kyverna Therapeutics
Location: Remote (ideally based in Western region)
Travel: Approximately 50-70%

About Kyverna Therapeutics

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company dedicated to developing innovative cell therapies for patients suffering from autoimmune diseases. Guided by our core values – Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome – we are committed to transforming the future of treatment for autoimmune diseases and redefining what's possible in cell therapy.

Position Overview

Kyverna is seeking a Medical Science Liaison (MSL) or Senior Medical Science Liaison (Senior MSL) to join our Medical Affairs organization. This field-based scientific expert will engage with healthcare professionals, investigators, treatment centers, and Key Opinion Leaders (KOLs) focused on autoimmune diseases and cell therapy. The ideal candidate possesses strong scientific expertise, exceptional relationship-building skills, and experience with complex specialty therapies in biotechnology or pharmaceuticals. You will play a critical role in communicating scientific and clinical data, gathering field insights, and supporting the development of Kyverna’s CAR-T therapy programs.

Responsibilities:

Scientific Engagement & KOL Management:

• Identify, establish, and maintain high-quality scientific relationships with KOLs, investigators, academic medical centers, community physicians, pharmacists, nurses, and treatment centers within your assigned territory.
• Serve as a trusted scientific partner, providing fair-balanced, accurate, and compliant scientific exchange on disease states, treatment landscapes, Kyverna’s CAR-T programs, and emerging clinical data.
• Act as a primary scientific liaison for investigators interested in clinical research collaborations and investigator-initiated research discussions, in alignment with company policies.

Territory Strategy & Field Medical Planning:

• Develop and execute geography-specific Medical Affairs and KOL engagement plans aligned with therapeutic area objectives, investigator needs, and Kyverna’s medical strategy.
• Demonstrate ownership of your assigned territory through stakeholder mapping, prioritization, and proactive planning to influence the patient journey and support optimal therapeutic decision-making.
• Collaborate with other Kyverna field medical colleagues to share insights and coordinate external engagement approaches.

Clinical Development & Trial Support:

• Partner with Clinical Development and Clinical Operations colleagues to support Kyverna-sponsored clinical trials, including identifying potential trial sites, engaging with participating investigators, and supporting trial awareness and scientific dialogue.
• Contribute to efforts enhancing trial feasibility and enrollment through appropriate scientific engagement with investigators and treatment centers.

Medical Insights & Internal Collaboration:

• Capture and communicate timely, high-quality medical insights on the autoimmune and cell therapy landscape to internal stakeholders to inform strategy and evidence planning.
• Translate external scientific perspectives into actionable insights that guide medical, clinical, and development decision-making.
• Collaborate cross-functionally with Clinical Development, Clinical Operations, Regulatory Affairs, Commercial, Market Access, and Patient Services teams while maintaining strict non-promotional boundaries.

Scientific Representation & Compliance:

• Provide scientific support at national, regional, and local congresses, advisory boards, investigator meetings, and medical education forums.
• Respond compliantly to unsolicited medical information requests and serve as an internal and external scientific resource.
• Maintain current knowledge of therapeutic areas, treatment guidelines, clinical research processes, and cell therapy operational considerations, including treatment center workflows.
• Ensure timely completion of CRM documentation, administrative tasks, required training, and pharmacovigilance responsibilities (adverse event and product complaint reporting).
• Conduct all activities in full compliance with applicable laws, regulations, and company policies.

Qualifications:

• Advanced scientific or clinical degree required (MD, PharmD, PhD, DNP, NP, PA, or equivalent).
• For MSL: Doctorate degree OR Master’s degree & 3 years of Medical Affairs experience.
• For Senior MSL: Doctorate degree & 2 years of Medical Affairs experience OR Master’s degree & 6 years of Medical Affairs experience.
• Prior experience in cell therapy, CAR-T, immunology, rheumatology, nephrology, neurology, hematology/oncology, or rare diseases is strongly preferred.
• Strong understanding of clinical trial design, clinical development, and medical affairs functions.
• Experience engaging with academic medical centers, specialty treatment centers, and/or infusion centers is preferred.
• Ability to interpret and communicate complex scientific and clinical information to diverse audiences.
• Excellent presentation, communication, and interpersonal skills.
• Demonstrated ability to build strong external relationships and collaborate effectively across cross-functional teams.
• Comfortable operating within a fast-paced, high-growth biotechnology environment.
• Willingness and ability to travel extensively within the assigned geography.
• Experience supporting pre-commercial or launch-stage biotechnology organizations.
• Knowledge of autoimmune disease treatment landscapes and emerging cell therapy approaches.
• Experience supporting investigator-sponsored research and clinical trial recruitment initiatives.
• Familiarity with cell therapy operational concepts (e.g., chain of identity, chain of custody, treatment center workflows).

Salary Ranges:

• MSL: $170,000 - $185,000 USD annually
• Senior MSL: $190,000 - $210,000 USD annually

Note: This salary range is an estimate. Actual salary may vary based on individual factors. This position is also eligible for bonus, benefits, and participation in the Company’s stock plan.