Zone Director

MISSION:

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries into important medicines for patients. We are collaborative, creative, and experienced professionals seeking individuals who embody our values: care, be real, get it done, and have fun, seriously.

POSITION SUMMARY:

The Zone Director is a second-line field leader responsible for driving commercial performance, building 4 high-performing Region Business Director (RBD) teams, and ensuring execution excellence across the liver portfolio. This role translates national strategy into regional impact, with a strong emphasis on rare disease expertise, patient-centricity, and cross-functional leadership.

Assigned Area: ME, NH, VT, NY, RI, MA, CT, NJ, PA, DE, MD, D.C., VA, OH, MI, IN, TN, NC, SC, GA, FL

JOB FUNCTIONS/RESPONSIBILITIES:

Enterprise Leadership:

• Own and deliver Zone business performance across the liver portfolio with a strategic mindset.
• Drive change and innovation.
• Develop and execute zone-specific business plans aligned to national strategy.
• Analyze market trends, competitive dynamics, and performance data to inform actions.

Team Leadership & Development:

• Lead, coach, and develop first-line leaders to maximize team effectiveness.
• Build a strong leadership pipeline and succession plans.
• Foster a culture of accountability, engagement, and continuous improvement.

Execution Excellence:

• Ensure consistent and high-quality execution of brand strategy in the field.
• Monitor KPIs and drive disciplined performance management.
• Identify and scale best practices across regions.

Cross-Functional Collaboration:

• Partner with Marketing, Market Access, Medical Affairs, Patient Services, and Operations.
• Ensure alignment on strategy and coordinated execution.
• Provide field insights to inform brand planning and lifecycle strategy.

Market & Customer Engagement:

• Maintain strategic relationships with Key Opinion Leaders (KOLs) and top accounts.
• Understand regional nuances in referral patterns and treatment pathways.
• Support teams in navigating complex access and reimbursement environments.

Compliance & Ethical Leadership:

• Ensure all activities comply with regulatory, legal, and company policies.
• Model integrity and patient-first decision-making.
• Reinforce a culture of compliance across the organization.

QUALIFICATIONS:

Education/Experience:

• Bachelor’s degree required; advanced degree preferred (MBA, etc.).
• 7+ years of pharmaceutical/biotech experience, with a minimum of 5 years of leadership experience.
• Successful experience leading leaders (second-line leadership) highly desired.
• Significant rare disease and/or specialty experience.
• Experience in rare liver disease is a plus.
• Proven success in product launches, ideally with first-in-class therapies and in competitive markets.
• Demonstrated ability to build, lead, train, and develop high-performing teams.
• Proven success in sales leadership roles with the ability to inspire, influence, and align teams.
• Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and access to therapies.
• Strong leadership presence.
• Strong understanding of market access, payer dynamics, and patient services.
• Demonstrated ability to lead in a matrixed organization.
• High integrity, ethical standards, and commitment to compliance.
• Thrives in a fast-paced, dynamic, and collaborative environment.
• Able to travel frequently (up to 70% overnight travel) and possesses a valid driver's license.

#LI-REMOTE

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and compliance with all applicable laws. We provide reasonable accommodation for qualified individuals with disabilities.