Zone Director - Mirum Pharmaceuticals

Company: Mirum Pharmaceuticals

Location: WA, OR, CA, NV, AZ, UT, ID MT, WY, CO, NM, TX, KS, SD, ND, OK. LA, AR, MO, IA, MN, WI, IL, KY, MS, AL

About Mirum Pharmaceuticals:

Mirum Pharmaceuticals is a dedicated biopharmaceutical company focused on transforming the treatment of rare diseases. We are driven by a passion for advancing scientific discoveries into vital medicines for patients. Our team comprises collaborative, creative, and experienced professionals who embody our core values: care, be real, get it done, and have fun, seriously.

About the Role:

The Zone Director is a crucial second-line field leadership position responsible for driving commercial performance, building four high-performing Region Business Director (RBD) teams, and ensuring execution excellence across our liver portfolio. This role is pivotal in translating national strategy into regional impact, with a strong emphasis on rare disease expertise, patient-centricity, and cross-functional leadership.

Key Responsibilities:

• Enterprise Leadership: Own and deliver Zone business performance for the liver portfolio with a strategic, big-picture mindset. Drive change and innovation, develop and execute zone-specific business plans aligned with national strategy, and analyze market trends and competitive dynamics to inform actions.
• Team Leadership & Development: Lead, coach, and develop first-line leaders to maximize team effectiveness. Build a strong leadership pipeline and succession plans, fostering a culture of accountability, engagement, and continuous improvement.
• Execution Excellence: Ensure consistent and high-quality execution of brand strategy in the field. Monitor KPIs, drive disciplined performance management, and identify and scale best practices across regions.
• Cross-Functional Collaboration: Partner with Marketing, Market Access, Medical Affairs, Patient Services, and Operations to ensure strategic alignment and coordinated execution. Provide field insights to inform brand planning and lifecycle strategy.
• Market & Customer Engagement: Maintain strategic relationships with Key Opinion Leaders (KOLs) and top accounts. Understand regional nuances in referral patterns and treatment pathways, and support teams in navigating complex access and reimbursement environments.
• Compliance & Ethical Leadership: Ensure all activities comply with regulatory, legal, and company policies. Model integrity and patient-first decision-making, reinforcing a culture of compliance across the organization.

Qualifications:

• Bachelor’s degree required; advanced degree (MBA, etc.) preferred.
• 7+ years of pharmaceutical/biotech experience, with a minimum of 5 years of leadership experience.
• Successful experience leading leaders (second-line leadership) is highly desired.
• Significant rare disease and/or specialty experience; experience in rare liver disease is a plus.
• Proven success in product launches, ideally with first-in-class therapies and in competitive markets.
• Demonstrated ability to build, lead, train, and develop high-performing teams.
• Proven success in sales leadership roles with the ability to inspire, influence, and align teams.
• Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and access to therapies.
• Strong leadership presence with the ability to inspire, influence, and align teams.
• Strong understanding of market access, payer dynamics, and patient services.
• Demonstrated ability to lead in a matrixed organization.
• High integrity, ethical standards, and commitment to compliance.
• Ability to thrive in a fast-paced, dynamic, and collaborative environment.
• Willingness to travel frequently (up to 70% overnight travel) and possess a valid driver’s license.

Benefits:

• [Not Specified]

Equal Opportunity Employer:

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State, and Local laws that prohibit employment discrimination. We provide reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.